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L-Citrulline: Research, Dosing, and Where to Buy in 2026

A research-first profile for L-Citrulline (lcitrilline), aggregating mechanism notes, transcript dosing mentions, vendor recommendations, and PubMed-indexed literature without presenting medical guidance.

Quick Answer

L-Citrulline is a research compound profiled here from named-expert transcripts and peer-reviewed literature, without medical guidance. As of July 2026, The Peptide Wiki aggregates 8 PubMed-cited papers, 2 attributed expert mentions, 3 transcript dosing protocols, and 1 referenced vendor for L-Citrulline, each linked to its source.

Key Facts
Supplement
  • Also indexed as lcitrilline.
  • 3 aggregated dosing-protocol mentions from source transcripts.
  • 8 PubMed-indexed citations listed in the research table below.
  • 1 vendor recommendation captured from named experts.
Sourced to expert
Check vendor COA
Verify dose w/ clinician

What is L-Citrulline?

Research compound aggregated from creator and literature mentions. No direct disease-treatment claims are made on this page.

Experts on background and overview · 1 cited mention

"You can take L-citrulline malate for that or beta-alanine or inject carnosine or take baking soda, sodium bicarbonate."
Vigorous Steve · Ozempic Issues, Injectable Anadrol, Shrink Gyno, Hypo On... @ 19:20

L-Citrulline Dosing Protocols

The entries below are transcript-derived dosing mentions. They are preserved for research context and are not medical advice.

SpeakerSourceTimestampProtocolEvidence
Vigorous Steve Increase Energy With Lactate Removing Compounds, Carbohydrate... 00:00:51 Steve reported: 4,000 to 5,000 mg per scoop (dose found in Gorilla Mode pre-workouts: Kuramote, Nitric, Base, Lightning) anecdotal
>> How To Improve The Pumps In The Gym?! 00:00:16 Users report taking citrulline malate around 6 g before workout as a nitric oxide precursor to support vasodilation and gym pump effects. anecdotal
VigorousClips Increase Energy With Lactate Removing Compounds, Carbohydrate... 00:00:49 Host reported 4,000 to 5,000 mg per single scoop pre-workout as effective anecdotal

Where to Buy L-Citrulline in 2026

Side Effects and Safety

Anecdotal reports and study-level observations vary by route, dose, and individual. This page does not provide medical advice. Consult a qualified clinician before any research use.

What Experts Say

1 expert across our source library discuss L-Citrulline. Each entry is that expert’s most context-rich mention: click to watch it at the exact timestamp in the original video. Quotes are also emitted as Schema.org Quotation JSON-LD for AI assistants.

  1. Vigorous Steve · Ozempic Issues, Injectable Anadrol, Shrink Gyno, Hypo...Watch @ 19:20 ↗

    “You can take L-citrulline malate for that or beta-alanine or inject carnosine or take baking soda, sodium bicarbonate.”

User Reviews

User reviews aggregator coming Q3 2026 (Reddit + YouTube comments + Discord research notes). Until then, see the expert quote section above and PubMed citations below.

Research Efficacy Snapshot

Published efficacy percentages cited in PubMed trials and named-expert reports about L-Citrulline. Each line links to the original source.

  • "In prevention trials, L-arginine was associated with a reduced risk of pre-eclampsia (relative risk [RR] 0.52; 95% confidence interval [CI], 0.35, 0.78; low-certainty evidence, four trials) and severe pre-eclampsia (RR 0.23; 95% CI, 0.09, 0.55; low-certainty evidence, three trials)." · Makama M et al, 2025 PubMed
  • "In treatment trials, L-arginine may reduce mean systolic blood pressure (MD -5.64 mmHg; 95% CI, -10.66, -0.62; very low-certainty evidence, three trials) and fetal growth restriction (RR 0.46; 95% CI, 0.26, 0.81; low-certainty evidence, two trials)." · Makama M et al, 2025 PubMed

Research and Studies

8 PubMed-indexed papers reference L-Citrulline. Top 8 shown.

Frequently Asked Questions

Is L-Citrulline FDA-approved?

L-Citrulline is presented on this page as a research compound. FDA approval status, scheduling, and state-specific rules may apply and change. Verify current regulatory status before any decision.

What dosing is reported for L-Citrulline?

This page aggregates 3 dosing-protocol mention(s) from named-expert transcripts, each linked to a verbatim source timestamp. See the Dosing Protocols table above. Mentions are anecdotal, not medical advice.

Where can I buy L-Citrulline?

1 vendor recommendation(s) are tracked in our directory, sourced from named-expert mentions. See the Where to Buy section above. Always verify COA and current regulatory status.

How much research has been published on L-Citrulline?

8 PubMed-indexed paper(s) reference L-Citrulline in our current research feed. See the Research and Studies section above for citations.