Sobetirome (GC-1): Research, Dosing, and Where to Buy in 2026
A research-first profile for Sobetirome (GC-1) (sobuterol, so own GC-1, GC-1), aggregating mechanism notes, transcript dosing mentions, vendor recommendations, and PubMed-indexed literature without presenting medical guidance.
Sobetirome (GC-1) is a research compound profiled here from named-expert transcripts and peer-reviewed literature, without medical guidance. As of July 2026, The Peptide Wiki aggregates 8 PubMed-cited papers, 5 transcript dosing protocols, and 2 referenced vendors for Sobetirome (GC-1), each linked to its source.
- Also indexed as sobuterol, so own GC-1, GC-1.
- 5 aggregated dosing-protocol mentions from source transcripts.
- 8 PubMed-indexed citations listed in the research table below.
- 2 vendor recommendations captured from named experts.
What is Sobetirome (GC-1)?
Research compound aggregated from creator and literature mentions. No direct disease-treatment claims are made on this page.
Sobetirome (GC-1) Dosing Protocols
The entries below are transcript-derived dosing mentions. They are preserved for research context and are not medical advice.
| Speaker | Source | Timestamp | Protocol | Evidence |
|---|---|---|---|---|
| VigorousClips | The Better Option Than T3 For Fat Loss?!? | 00:03:34 | 15-30 mcg/kg body weight orally daily for 6 weeks in rats; speaker reported calculating a theoretical human equivalent dose of 0.24-0.49 mcg/kg, or approximately 24-49 mcg for a 100 kg person, based on standard scaling methodologies. Sobetirome-gc-1 is a research compound not intended for human consumption. | anecdotal |
| VigorousClips | Take This With Your TUDCA For The Best Results | 00:01:49 | Comparison dose: 5.4 nmol/kg/day from animal model, estimated as about 0.14 mcg/kg GC-1; route in animal model intraperitoneal, compared by speaker to intramuscular injection, while humans would likely take orally. | anecdotal |
| VigorousClips | How Tren Can Melt Fat And Reveal Your Hidden Abs | 00:05:37 | Users reported dosing ranges of 25 mcg to 100 mcg daily (upon waking or before bed); anecdotal reports indicated tolerance of up to 200 mcg/day without elevated heart rate; individual responses vary. | anecdotal |
| VigorousClips | These Fat Burners Won't Give You A Heart Attack, Non-Stimulant... | 00:05:18 | Users report dosing sobetirome-gc-1 at ranges comparable to T3 (approximately 25-100 mcg), with anecdotal accounts of non-stimulatory effects compared to T3 supplementation. | anecdotal |
| VigorousClips | How To Take Sobetirome For Better Energy, Fat Loss, And Lipid Levels... | 00:06:10 | Many users reportedly start at 50-100 mcg GC-1 daily; speaker says starting at 50 mcg is doable based on anecdotes and personal experience. | anecdotal |
Where to Buy Sobetirome (GC-1) in 2026
Amino Asylum
Visit vendor → View profile →Recommended by Speaker at 00:05:34.
Modern Aminos
Visit vendor → View profile →Recommended by Speaker at 00:05:37.
Side Effects and Safety
Anecdotal reports and study-level observations vary by route, dose, and individual. This page does not provide medical advice. Consult a qualified clinician before any research use.
User Reviews
User reviews aggregator coming Q3 2026 (Reddit + YouTube comments + Discord research notes). Until then, see the expert quote section above and PubMed citations below.
Research Efficacy Snapshot
Published efficacy percentages cited in PubMed trials and named-expert reports about Sobetirome (GC-1). Each line links to the original source.
- "Whereas in the GC-1 group, heart concentrations are 93.8% lower compared to liver concentrations, which is 16-fold lower, and muscle concentrations are about 87.2% lower compared to liver concentrations, which is eight-fold lower." · speaker_1 on "How To Take Sobetirome For Better Energy, Fat Loss, And Lipi" @ 0:50
- "Studies showed it decreased oligodendrocyte progenitor cells by approximately 25 to 33% while increasing pre-myelinating oligodendrocytes by approximately 50 to 180%." · speaker_1 on "The Better Option Than T3 For Fat Loss?!?" @ 1:59
- "When you compare that to Sobetirome GC-1 with an established half-life of 7.2 hours and oral bioavailability of 92% that is significantly higher, the molecular weight is approximately half that of T3 at 328.408 Daltons." · speaker on "Why You Should Consider Using Thyroid Hormones | GC-1 Sobeti" @ 2:40
- "Animal model research indicated Sabaterone reduced fat mass by 15% to 23%, reduced retroperitoneal fat pads by 48%, and increased oxygen consumption by 46% to 88%, without affecting serum T3 levels, lean muscle mass, cardiac tissue, or food intake." · speaker_1 on "The Better Option Than T3 For Fat Loss?!?" @ 3:08
- "In a 48-animal study, GC-1 reduced serum HDL levels by increasing HDL receptor SR-B1 in the liver by approximately 240%." · Speaker 1 on "Take This With Your TUDCA For The Best Results" @ 3:32
- "increased by 45% in the 48 animal GC-1 group, and by 30% in the 48 animal T3 group, and cytochrome P457A1 messenger RNA levels, the enzyme responsible for bile acid synthesis in the liver from cholesterol, increased by 225% in the GC-1 group, whereas it only increased by 175% in the T3 group." · Speaker 1 on "Take This With Your TUDCA For The Best Results" @ 5:42
- "Comparing molecule for molecule the molar equivalent dosages, GC-1 increased oxygen consumption significantly more than T3, an increase of approximately 46 to 88% compared to the control groups, whereas T3 increased it by approximately 44 to 46%." · speaker_1 on "The Better Option Than T3 For Fat Loss?!?" @ 7:23
- "Research indicates GC-1 increases oxygen consumption by 53 to 90%." · speaker_1 on "The Better Option Than T3 For Fat Loss?!?" @ 9:17
Research and Studies
8 PubMed-indexed papers reference Sobetirome (GC-1). Top 8 shown.
Legal Status
Sobetirome (GC-1) is presented here as a research compound. FDA approval status, scheduling, WADA status, and state-specific telehealth rules may apply. Always verify current regulatory status. Last verified: 2026-07-09.
Frequently Asked Questions
Is Sobetirome (GC-1) FDA-approved?
Sobetirome (GC-1) is presented on this page as a research compound. FDA approval status, scheduling, and state-specific rules may apply and change. Verify current regulatory status before any decision.
What dosing is reported for Sobetirome (GC-1)?
This page aggregates 5 dosing-protocol mention(s) from named-expert transcripts, each linked to a verbatim source timestamp. See the Dosing Protocols table above. Mentions are anecdotal, not medical advice.
Where can I buy Sobetirome (GC-1)?
2 vendor recommendation(s) are tracked in our directory, sourced from named-expert mentions. See the Where to Buy section above. Always verify COA and current regulatory status.
How much research has been published on Sobetirome (GC-1)?
8 PubMed-indexed paper(s) reference Sobetirome (GC-1) in our current research feed. See the Research and Studies section above for citations.