Synephrine: Research, Dosing, and Where to Buy in 2026
A research-first profile for Synephrine, aggregating mechanism notes, transcript dosing mentions, vendor recommendations, and PubMed-indexed literature without presenting medical guidance.
Synephrine is a research compound profiled here from named-expert transcripts and peer-reviewed literature, without medical guidance. As of July 2026, The Peptide Wiki aggregates 8 PubMed-cited papers, and 1 transcript dosing protocol for Synephrine, each linked to its source.
- 1 aggregated dosing-protocol mention from source transcripts.
- 8 PubMed-indexed citations listed in the research table below.
- 0 vendor recommendations captured from named experts.
What is Synephrine?
Research compound aggregated from creator and literature mentions. No direct disease-treatment claims are made on this page.
Synephrine Dosing Protocols
The entries below are transcript-derived dosing mentions. They are preserved for research context and are not medical advice.
| Speaker | Source | Timestamp | Protocol | Evidence |
|---|---|---|---|---|
| Vigorous Steve | Super Intense Stimulant Based Fat Burners (Burn Fat Fast!) | 00:04:10 | VigorousSteve reported using 10 to 20 mg per day, split into a couple servings. | anecdotal |
Where to Buy Synephrine in 2026
No tracked vendor recommendations for Synephrine yet. See our vendor directory.
Side Effects and Safety
Anecdotal reports and study-level observations vary by route, dose, and individual. This page does not provide medical advice. Consult a qualified clinician before any research use.
User Reviews
User reviews aggregator coming Q3 2026 (Reddit + YouTube comments + Discord research notes). Until then, see the expert quote section above and PubMed citations below.
Research Efficacy Snapshot
Published efficacy percentages cited in PubMed trials and named-expert reports about Synephrine. Each line links to the original source.
- "The adrenergic effect of bitter orange is caused by the presence of R-(-)-psynephrine, making up about 90% or more of the total protoalkaloids." · Perova I et al, 2021 PubMed
- "Dry bitter orange fruit extracts, standardized to synephrine content, which can vary from 4 to 98%, are used in the production of DS and SF." · Perova I et al, 2021 PubMed
- "This effect has been observed in a range of exercise workloads between 30% and 80% of peak oxygen uptake (VO2peak)." · Ruiz-Moreno C et al, 2021 PubMed
Research and Studies
8 PubMed-indexed papers reference Synephrine. Top 8 shown.
Legal Status
Synephrine is presented here as a research compound. FDA approval status, scheduling, WADA status, and state-specific telehealth rules may apply. Always verify current regulatory status. Last verified: 2026-07-09.
Frequently Asked Questions
Is Synephrine FDA-approved?
Synephrine is presented on this page as a research compound. FDA approval status, scheduling, and state-specific rules may apply and change. Verify current regulatory status before any decision.
What dosing is reported for Synephrine?
This page aggregates 1 dosing-protocol mention(s) from named-expert transcripts, each linked to a verbatim source timestamp. See the Dosing Protocols table above. Mentions are anecdotal, not medical advice.
How much research has been published on Synephrine?
8 PubMed-indexed paper(s) reference Synephrine in our current research feed. See the Research and Studies section above for citations.